Understanding Cold Agglutinin Disease (CAD)

Cold Agglutinin Disease (CAD) is a rare autoimmune disorder that affects the immune system's ability to function properly. When exposed to cold temperatures, CAD causes the body's immune system to produce cold agglutinins – antibodies that attack red blood cells. This can lead to a range of symptoms and complications, as well as impair circulation and cause tissue damage.

CAD can have a significant impact on an individual's overall health and quality of life. It often presents with symptoms such as fatigue, weakness, shortness of breath, and color changes in the extremities.